MyGlycotest routinely map N-linked glycans to monitor changes at each step of biolanufacturing.
Glycotests are multi-lectin solid phase assays that are customized to target antibody, gene & cell therapies. They :
- work on intact proteins or cells : no release of glycans nor labeling is needed
- identify glycosylation changes in dozen of samples within a working day
- deliver the glycan signature of the product at line and on-line
- reduce costs compared to existing microarrays and metabolomics
Various formats are available. Each format can be customized to the needed product. They can map up 6 levels of heterogeneity in N-linked glycans. O-linked glycans and specific carbohydrate antigens can also be estimated using special design.